Lambert Center for the Study of Medicinal Cannabis & Hemp

Research

Javad Parvizi

Cannabinoids Bacterial Killing In Vitro With and Without Antibiotics
The study will aim to characterize cannabidiol as a potential antibacterial and helper compound in preclinical models of irrigation solution and bone cement release against resistant bacteria in combination or without commonly used antibiotics (vancomycin, tobramycin, bacitracin, gentamicin and cefazolin).

Javad Parvizi, MD, FRCS - Director of Clinical Research at the Rothman Orthopaedic Institute, James Edwards Professor Chair of Orthopaedics at Thomas Jefferson University; and Emanuele Chisari, MD, Post-Doc Research Fellow, Orthopedic Surgery, Rothman Orthopaedic Institute

David Axelrod

Observational Study in Cannabis and Sickle Cell Disease Patients With Chronic Pain
The study will look at the quality of life, functional status and pain scores of sickle cell disease patients who are taking opioids only, cannabis only, and opioids and cannabis.

David Axelrod, MD - Internal Medicine Specialist, Comprehensive Sickle Cell Program, Thomas Jefferson University; and Kimberly Binsfeld, MS, Director of Research, Lambert Center for the Study of Medicinal Cannabis and Hemp, Thomas Jefferson University Hospitals

Roseann Schaaf

Cannabis Use in Autism Spectrum Disorder (ASD)
The study will survey a group of parents of children with ASD to assess their level of knowledge and interest in cannabis use for their child and to gauge their interest in participating in future research studies.

Roseann Schaaf, PhD, OTR/L, FAOTA - Director, Occupational Therapy, Jefferson's Autism Center of Excellence, Jefferson College of Rehabilitation Sciences, Faber Institute for Neurosciences, Thomas Jefferson University; and Daniel Graves, PhD, FACRM, Associate Dean of Research, Vice Chairman for Research, College of Rehabilitation Medicine, Department of Rehabilitation, Thomas Jefferson University

Daniel Graves

Known Group Analysis of Sensitivity of Clinical Measures for Cannabis Trials for Persons With Spinal Cord Injury
The study will be an in-depth investigation of the differences in measures of physical health, quality of life, community participation and cognition in self-selected groups of current cannabis users, past cannabis users and non-cannabis users.

Daniel Graves, PhD, FACRM - Associate Dean of Research, Vice Chairman for Research, College of Rehabilitation Medicine, Department of Rehabilitation, Thomas Jefferson University

Michael Marmura

Medical Marijuana in the Management of Headache Disorders
This retrospective chart review will record the demographics and clinical features of patients at a tertiary headache center enrolled in a medical cannabis clinic and look at outcomes of treatment.

Michael Marmura, MD, FAHS - Associate Professor, Director of Outpatient Operations, Jefferson Headache Center, Thomas Jefferson University; Co-Investigators: Angela Hou, MD; Neurology (Headache); Claire Ceriani, MD Neurology (Headache); and Courtney White, MD; Neurology

Ronald Kander

Industrial Hemp: Manufacture and Characterization of Cellulose Nanocrystals and Cellulose Nanofibrils
Funding will support the existing PA Manufacturing Fellows Initiatives, specifically working with local Pennsylvania industries. The grant supports work with Coexist to develop a line of hemp-reinforced polymer 3D printing filaments that are biodegradable and sustainable and have superior mechanical and physical properties, as well as work with Eastern Hemp Company to develop a line of hemp-reinforced polymer composite injection molding pellets.

Ronald Kander, PhD - Associate Provost, Applied Science; Dean, Kanbar College of Design, Engineering and Commerce, Thomas Jefferson University

External Research Studies

Mahmoud ElSohly

Development of Oral Dosage Formulation Using Hot Melt Casting as a Promising Method to Enhance Solubility and Bioavailability of Cannabidiol

Mahmoud ElSohly, PhD - PI, and Co-Investigator: Eman Ashour, PhD, University of Mississippi

Eric Marsh

Test the Effectiveness of a Novel Cannabinoid in Two Well Established Rodent Models of Early Onset Seizures

Eric Marsh, MD, PhD, Children’s Hospital of Philadelphia

Ryan Vandrey

Short- and Long-Term Effects of Medicinal Use of Cannabis by Individuals with Anxiety and Depression

Ryan Vandrey, PhD, Behavioral Pharmacology Research Unit, Johns Hopkins University School of Medicine

2019 Research

Development of Oral Dosage Formulation Using Hot Melt Casting as a Promising Method to Enhance Solubility and Bioavailability of Cannabidiol
Mahmoud A. ElSohly, PhD, University of Mississippi

CBD Mouse Study Protocol (Effectiveness of a Novel Cannabiniod in Two Well Established Rodent Models of Early Onset Seizures)
Eric Marsh, MD, PhD, Children’s Hospital of Philadelphia

Short- and Long-Term Effects of Medicinal Use of Cannabis by Individuals with Anxiety and Depression
Ryan Vandrey, PhD, Johns Hopkins University