Observational Study in Cannabis and Sickle Cell Disease Patients With Chronic Pain
The study will look at the quality of life, functional status and pain scores of sickle cell disease patients who are taking opioids only, cannabis only, and opioids and cannabis.

David Axelrod, MD - Internal Medicine Specialist, Comprehensive Sickle Cell Program, Thomas Jefferson University; and Kimberly Binsfeld, MS, Director of Research, Lambert Center for the Study of Medicinal Cannabis and Hemp, Thomas Jefferson University Hospitals

Cannabis Use in Autism Spectrum Disorder (ASD)
The study will survey a group of parents of children with ASD to assess their level of knowledge and interest in cannabis use for their child and to gauge their interest in participating in future research studies.

Roseann Schaaf, PhD, OTR/L, FAOTA - Director, Occupational Therapy, Jefferson's Autism Center of Excellence, Jefferson College of Rehabilitation Sciences, Faber Institute for Neurosciences, Thomas Jefferson University; and Daniel Graves, PhD, FACRM, Associate Dean of Research, Vice Chairman for Research, College of Rehabilitation Medicine, Department of Rehabilitation, Thomas Jefferson University

Known Group Analysis of Sensitivity of Clinical Measures for Cannabis Trials for Persons With Spinal Cord Injury
The study will be an in-depth investigation of the differences in measures of physical health, quality of life, community participation and cognition in self-selected groups of current cannabis users, past cannabis users and non-cannabis users.

Daniel Graves, PhD, FACRM - Associate Dean of Research, Vice Chairman for Research, College of Rehabilitation Medicine, Department of Rehabilitation, Thomas Jefferson University

Medical Marijuana in the Management of Headache Disorders
This retrospective chart review will record the demographics and clinical features of patients at a tertiary headache center enrolled in a medical cannabis clinic and look at outcomes of treatment.

Michael Marmura, MD, FAHS - Associate Professor, Director of Outpatient Operations, Jefferson Headache Center, Thomas Jefferson University; Co-Investigators: Angela Hou, MD; Neurology (Headache); Claire Ceriani, MD Neurology (Headache); and Courtney White, MD; Neurology

Industrial Hemp: Manufacture and Characterization of Cellulose Nanocrystals and Cellulose Nanofibrils
Funding will support the existing PA Manufacturing Fellows Initiatives, specifically working with local Pennsylvania industries. The grant supports work with Coexist to develop a line of hemp-reinforced polymer 3D printing filaments that are biodegradable and sustainable and have superior mechanical and physical properties, as well as work with Eastern Hemp Company to develop a line of hemp-reinforced polymer composite injection molding pellets.

Ronald Kander, PhD - Associate Provost, Applied Science; Dean, Kanbar College of Design, Engineering and Commerce, Thomas Jefferson University

Development of Oral Dosage Formulation Using Hot Melt Casting as a Promising Method to Enhance Solubility and Bioavailability of Cannabidiol

Mahmoud ElSohly, PhD - PI, and Co-Investigator: Eman Ashour, PhD, University of Mississippi

Test the Effectiveness of a Novel Cannabinoid in Two Well Established Rodent Models of Early Onset Seizures

Eric Marsh, MD, PhD, Children’s Hospital of Philadelphia

Short- and Long-Term Effects of Medicinal Use of Cannabis by Individuals with Anxiety and Depression

Ryan Vandrey, PhD, Behavioral Pharmacology Research Unit, Johns Hopkins University School of Medicine