Biochemistry, Structural & Molecular Biology


College of Life Sciences


Doctor of Philosophy


Center City


On Campus


4 - 5 Years

Current Students


Candice Bizzaro

Laboratory: Matthew Schiewer, PhD

Project: TBD

Annie Londregan

Laboratory: Scott Waldman, MD, PhD

Project: TBD

Brittany Mahon

Laboratory: Christine Eischen, PhD

Project: TBD

Genevieve Lewis (MD/PhD)

Laboratory: Emad Alnermi, PhD

Project: My project aims to elucidate the role of WNK1 signaling in macrophage inflammasome activation, and how deregulation of this pathway leads to various inflammation-mediated pathologies.

Henri McGuigan

Laboratory: Ya-Ming Hou, PhD

Project: TBD

Hailey Shankle

Laboratory: Steven McMahon, PhD

Project: TBD

Viktoriia Sokolova

Laboratory: Dmitry Temiakov, PhD

Project: TBD

Adi Caspi

Laboratory: Scott Waldman, MD, PhD

Project: I study the guanylyl cyclase C (GCC) signaling axis in the context of colorectal cancer. 

Melanie Goetz

Laboratory: Sara Meyer, PhD

Project: Studying the role of p300 in epigenetic mutant acute myeloid leukemia (AML)

Andrew Isopi

Laboratory: Holly Ramage, PhD

Project: Andrew is researching innate immune signaling and functional proteomics during Flavivirus infection. 

Lily Thompson

Laboratory: Elise Fouquerel, PhD

Project: My project involves investigating the effect of oxidative stress at the centromere and how this contributes to chromosomal instability.

Jenny Carey

Laboratory: Lin Guo, PhD

Project: My project focuses on studying protein phase separation of ALS-associated protein FUS and developing RNAs to reverse aberrant phase transition.

Justin Gumas

Laboratory: Yohei Kirino, PhD

Project: Identification and functional characterization of angiogenin-induced 2’,3’-cyclic phosphate-containing RNAs in the context of ALS

Karl Herbine

Laboratory: Dmitry Temiakov, PhD

Project: The purpose of my thesis project is to understand the underlying molecular mechanisms of transcription initiation and processive elongation in human mitochondria using structural methods.

Natalie Laspata

Laboratory: Elise Fouquerel, PhD

Project: I study the role of DNA repair proteins in the maintenance of telomere integrity and genome stability.

Hannah Hoag Lee

Laboratory: Elda Grabocka, PhD

Project: I am currently researching the mechanisms and consequences of stress granules in the microenvironment of pancreatic cancer.  Specifically, I am examining how stress granules promote the activation of a particular phenotype of cancer-associated fibroblasts.

Ruoyu Yang

Laboratory: Gino Cingolani, PhD

Project: Hepatitis B Virus (HBV) is a prevalent pathogen, but how it enters the nucleus remains unknown. My project is to test if HBV capsid shuttles through nuclear pore via classical nucleo-cytoplasmic transport.

Gina Buchel

Laboratory: Dmitry Temiakov, PhD

Project: Studying the molecular mechanisms underlying human mitochondrial transcription and replication using biochemical and structural approaches.

Victoria Frisbie

Laboratory: Erik Debler, PhD

Project: My project focuses on two methyltransferases essential to T. brucei’s survival and their recognition of Tb canonical and variant nucleosomes as substrates. To define this interaction, I use structural biochemistry techniques, such as enzymatic assays, x-ray footprinting, x-ray crystallography, and cryo-electron microscopy.

Mason Tracewell

Laboratory: Steven McMahon, PhD

Project: Investigating the mechanism behind USP22's impact on activator-driven transcription

Qingqing Cao

Laboratory: Andrew South, PhD

Project: ECM protein secretory defects when Type VII collagen is aberrant in RDEB dermal fibroblasts


Benjamin Barnhart
Laboratory of Rajanikanth Vadigepalli, PhD
Now:  Translational Research Solutions Scientist, Tempus Labs, Inc.


Steven Doll
Laboratory of Gino Cingolani, PhD
Now: TBD


Hannah Schapiro
Laboratory of Michael Root, MD, PhD
Now: Teaching Assistant Professor, Thomas Jefferson University



Emanuela Dylgjeri
Laboratory of Karen Knudsen, PhD
Now: Oncology Scientific Communications PhD Fellow, Janssen Scientific Affairs LLC. Part of Johnson & Johnson Pharmaceutical


Marina Farkas
Laboratory of Steven McMahon, PhD
Now: Postdoctoral Researcher, Josep Carreras Leukaemia Research Institute


Tyler Florio
Laboratory of Gino Cingolani, PhD
Now: Post-Doctoral Fellow, Children's Hospital of Philadelphia


Michael Ippolito
Laboratory of Jeffrey Benovic, PhD
Now: Post-Doctoral Fellow, Temple University


Dominic Lapadula
Laboratory of Jeffrey Benovic, PhD
Now: Post-Doctoral Fellow, Thomas Jefferson University


Amy Mandigo
Laboratory of Karen Knudsen, PhD
Now: Associate Scientist, Regeneron Pharmaceuticals


Lindsey Mayes-Hopfinger
Laboratory of Emad Alnemri, PhD
Now: Senior Scientist, Melior Discovery


Alison Moss
Laboratory of Rajanikanth Vadigepalli, PhD
Now: Computational Biologist, Rajant Health Inc.


Austin Parrish
Laboratory of Rajanikanth Vadigepalli, PhD
Now: Associate Data Scientist, RxDataScience


Azadeh Sarfallah
Laboratory of Dmitry Temiakov, PhD
Now: Post-Doctoral Fellow, University of Pennsylvania


Sarah Sulon
Laboratory of Jeffrey Benovic, PhD
Now: Post-Doctoral Fellow, University of Pennsylvania


Nicholas Swanson
Laboratory of Gino Cingolani, PhD
Now: Post-Doctoral Associate, Massachusetts Institute of Technology (MIT)


Halley Washburn
Laboratory of Matthew Dalva, PhD
Now: Post-Doctoral Fellow, Thomas Jefferson University



Samantha Brown
Laboratory of Jonathan Brody, PhD
Now: Research Scientist, Code Biotherapeutics


Mai Nguyen
Laboratory of Andrew Aplin, PhD
Now: Oncology Scientist/Medical Writer, National Comprehensive Cancer Network® (NCCN®)


Sheera Rosenbaum
Laboratory of Andrew Aplin, PhD
Now: Postdoctoral Fellow, University of Colorado Denver Anschutz Medical Campus