Division of Nephrology
Leadership
Positions:
- Director, Division of Nephrology
- Robert L. Capizzi Professor in Medicine
Organization:
Department of Medicine
Email:
Jerry.McCauley@jefferson.edu
Contact
833 Chestnut Strret
Suite 700
Philadelphia, PA 19107
Contact Number(s):
Research Activities
Our strong clinical research program, especially in the fields of acute kidney injury and hypertension, has been complemented by our growing basic research program in regulation of ion transport. We have obtained extramural funding for a broad range of clinical research projects in the areas of diabetic nephropathy, dialysis, nutrition and renal transplantation. Our NIH funded basic science research is focused on hypertension and regulation of ion transplant by FXYD proteins.
Bonita Falkner, MD
Research interests include the genetic basis of essential hypertension, insulin resistance and obesity.
Publications
- Pediatric Primary Hypertension: An Underrecognized Condition: A Scientific Statement from the American Heart Association
- Insulin Resistance and Other Mechanisms of Obesity Hypertension
- Development of Blood Pressure Norms and Definition of Hypertension in Children
- Cardiovascular Risk Factors and Target Organ Damage in Adolescents: The SHIP AHOY Study
- The enigma of primary hypertension in childhood
- Association of Blood Pressure-Related Increase in Vascular Stiffness on Other Measures of Target Organ Damage in Youth
- Approach to Hypertension in Adolescents and Young Adults
- Macrophage and adipocyte interaction as a source of inflammation in kidney disease
- Primary Hypertension Beginning in Childhood and Risk for Future Cardiovascular Disease
- Pediatric and Adult Ambulatory Blood Pressure Thresholds and Blood Pressure Load as Predictors of Left Ventricular Hypertrophy in Adolescents
- Management of Stage 1 Hypertension in Adults With a Low 10-Year Risk for Cardiovascular Disease: Filling a Guidance Gap: A Scientific Statement From the American Heart Association
- The USPSTF call to inaction on blood pressure screening in children and adolescents
- Life-Course Implications of Pediatric Risk Factors for Cardiovascular Disease
- Renal Physiology for Primary Care Clinicians
- Blood pressure unknowns of sickle cell disease in children
- Maternal and gestational influences on childhood blood pressure
- What about Stage 1 Hypertension in Young Adults?
- Subclinical Systolic and Diastolic Dysfunction Is Evident in Youth with Elevated Blood Pressure
- Primordial Prevention of High Blood Pressure in Childhood: An Opportunity Not to be Missed
- Association of blood pressure level with left ventricular mass in adolescents: SHIP AHOY
Maria P. Martinez Cantarin, MD
Research interests include Adipose tissue inflammation, kidney disease and transplant associated hyperglycemia.
Publications
- Adipose tissue metabolic changes in chronic kidney disease
- “Saving lives with nirmatrelvir/ritonavir one transplant patient at a time”
- Uremic Myopathy and Mitochondrial Dysfunction in Kidney Disease
- Macrophage and adipocyte interaction as a source of inflammation in kidney disease
- Diabetes in Kidney Transplantation
- Anemia in Chronic Kidney Disease
- Outcomes of COVID-19-positive kidney transplant recipients: A single-center experience
- Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects
- Correction to: Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects (Clinical Drug Investigation, (2019), 10.1007/s40261-019-00764-x)
- Kidney Support and Perioperative Care in Kidney Transplantation
- Patient Selection and Pretransplantation Care for Kidney Transplant Recipients
- Uremia induces adipose tissue inflammation and muscle mitochondrial dysfunction
- Association of inflammation prior to kidney transplantation with post-transplant diabetes mellitus
- Correlation of acute tubular injury in reperfusion biopsy with renal transplant outcomes
- Parathyroid Hormone-Related Peptide-Linked Hypercalcemia in a Melanoma Patient Treated with Ipilimumab: Hormone Source and Clinical and Metabolic Correlates
- Adiponectin receptor and adiponectin signaling in human tissue among patients with end-stage renal disease
- Reverse warburg effect in a patient with aggressive B-cell lymphoma: Is lactic acidosis a paraneoplastic syndrome?
- The adipose tissue production of adiponectin is increased in end-stage renal disease
- Relationship of adipokines with insulin sensitivity in African Americans
- Relationship of blood pressure and obesity with inflammatory cytokines among African Americans
Pooja Singh, MD
Research interests include immunological barriers in renal transplantation, sensitization and renal allograft failure management.
Publications
- Characterizing the risk of human leukocyte antigen-incompatible living donor kidney transplantation in older recipients
- Deceased-Donor Acute Kidney Injury and Acute Rejection in Kidney Transplant Recipients: A Multicenter Cohort
- Utilizing Social Media to Identify Potential Living Donors: Learning from US Living Donor Programs
- Optimising the use of telemedicine in a kidney transplant programme during the coronavirus disease 2019 pandemic
- Clinically adjudicated deceased donor acute kidney injury and graft outcomes
- Telehealth Use by Living Kidney Donor Transplant Programs During the COVID-19 Pandemic and Beyond: a Practical Approach
- Contemporary incidence and risk factors of post transplant Erythrocytosis in deceased donor kidney transplantation
- Post-transplant Diabetes Mellitus in Kidney Transplant Recipients: A Multicenter Study
- Deceased-donor acute kidney injury and bk polyomavirus in kidney transplant recipients
- COVID-19 in Solid Organ Transplantation: Disease Severity and Clinical Update
- Delayed graft function and acute rejection following HLA-incompatible living donor kidney transplantation
- Uromodulin to Osteopontin Ratio in Deceased Donor Urine Is Associated With Kidney Graft Outcomes
- Immune checkpoint inhibitor therapy-associated graft intolerance syndrome in a failed kidney transplant recipient
- Center-level Variation in HLA-incompatible Living Donor Kidney Transplantation Outcomes
- Preemptive Kidney Transplant: An Alternative to Dialysis
- Outcomes of COVID-19-positive kidney transplant recipients: A single-center experience
- An Unusual Case of Proteinuria in a Kidney Donor
- Urine Injury Biomarkers Are Not Associated with Kidney Transplant Failure
- Initial skin cancer screening for solid organ transplant recipients in the United States: Delphi method development of expert consensus guidelines
- The authors reply
Division Faculty Peer Reviewed Publications
- Design of the STRIVE-IPF trial- study of therapeutic plasma exchange, rituximab, and intravenous immunoglobulin for acute exacerbations of idiopathic pulmonary fibrosis
- Two DOT1 enzymes cooperatively mediate efficient ubiquitin-independent histone H3 lysine 76 tri-methylation in kinetoplastids
- Reaching the unheard: overcoming challenges in health research with hard-to-reach populations
- Retinal detachment
- Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms: A Propensity Score-Matched Analysis
- Strabismus management in retinoblastoma survivors
- Quality improvement in public–private partnerships in low- and middle-income countries: a systematic review
- Safety and tolerability of atogepant for the preventive treatment of migraine: a post hoc analysis of pooled data from four clinical trials
- Clinical practice guidelines in the management of pediatric foreign body aspiration and ingestion: a systematic evaluation using the AGREE II instrument
- Cervical cancer screening barriers and facilitators from the perspectives of women with a history of criminal-legal system involvement and substance use
- Virtual facilitation best practices and research priorities: a scoping review
- Horizontal transfer of miR-383 sensitise cells to cisplatin by targeting VEGFA-Akt signalling loop
- Association between postoperative changes in natremia and outcomes in patients undergoing elective craniotomy
- Circulating metabolic profile in idiopathic pulmonary fibrosis: data from the IPF-PRO Registry
- A new perspective on intervertebral disc calcification—from bench to bedside
- Microglia-derived exosomes modulate myelin regeneration via miR-615-5p/MYRF axis
- Early management of adult traumatic spinal cord injury in patients with polytrauma: a consensus and clinical recommendations jointly developed by the World Society of Emergency Surgery (WSES) & the European Association of Neurosurgical Societies (EANS)
- Standardized Pre-clinical Surgical Animal Model Protocol to Investigate the Cellular and Molecular Mechanisms of Ischemic Flap Healing
- Therapeutic antibodies for the prevention and treatment of cancer
- Does the Case Volume Experience of the Anesthesiologist Influence the Intraoperative Efficiency at All?