Research interests include the genetic basis of essential hypertension, insulin resistance and obesity.
Division of Nephrology
Research Activities
Our strong clinical research program, especially in the fields of acute kidney injury and hypertension, has been complemented by our growing basic research program in regulation of ion transport. We have obtained extramural funding for a broad range of clinical research projects in the areas of diabetic nephropathy, dialysis, nutrition and renal transplantation. Our NIH funded basic science research is focused on hypertension and regulation of ion transplant by FXYD proteins.
Publications
- Ambulatory blood pressure variability in prediction of target organ injury: the SHIP AHOY study
- A Multiomics Approach to Defining Target-Organ Injury in Youths With Primary Hypertension: The SHIP AHOY Cohort
- Use of censored data methods to estimate blood pressure percentiles in US adults
- Youth Blood Pressure and Target Organ Injury Markers: The SHIP AHOY Study
- Systolic Blood Pressure, Cardiovascular Health, and Neurocognition in Adolescents
- Cardiovascular Health Starts in the Womb
- Pediatric Primary Hypertension: An Underrecognized Condition: A Scientific Statement from the American Heart Association
- Development of Blood Pressure Norms and Definition of Hypertension in Children
- Insulin Resistance and Other Mechanisms of Obesity Hypertension
- Cardiovascular Risk Factors and Target Organ Damage in Adolescents: The SHIP AHOY Study
- The enigma of primary hypertension in childhood
- Association of Blood Pressure-Related Increase in Vascular Stiffness on Other Measures of Target Organ Damage in Youth
- Approach to Hypertension in Adolescents and Young Adults
- Macrophage and adipocyte interaction as a source of inflammation in kidney disease
- Primary Hypertension Beginning in Childhood and Risk for Future Cardiovascular Disease
- Pediatric and Adult Ambulatory Blood Pressure Thresholds and Blood Pressure Load as Predictors of Left Ventricular Hypertrophy in Adolescents
- The USPSTF call to inaction on blood pressure screening in children and adolescents
- Management of Stage 1 Hypertension in Adults With a Low 10-Year Risk for Cardiovascular Disease: Filling a Guidance Gap: A Scientific Statement From the American Heart Association
- Life-Course Implications of Pediatric Risk Factors for Cardiovascular Disease
- Renal Physiology for Primary Care Clinicians
Research interests include Adipose tissue inflammation, kidney disease and transplant associated hyperglycemia.
Publications
- TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis
- Parvovirus B19 Infection in Kidney Transplant Recipients
- Adipose tissue metabolic changes in chronic kidney disease
- “Saving lives with nirmatrelvir/ritonavir one transplant patient at a time”
- Uremic Myopathy and Mitochondrial Dysfunction in Kidney Disease
- Macrophage and adipocyte interaction as a source of inflammation in kidney disease
- Diabetes in Kidney Transplantation
- Anemia in Chronic Kidney Disease
- Outcomes of COVID-19-positive kidney transplant recipients: A single-center experience
- Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects
- Correction to: Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects (Clinical Drug Investigation, 10.1007/s40261-019-00764-x)
- Kidney Support and Perioperative Care in Kidney Transplantation
- Patient Selection and Pretransplantation Care for Kidney Transplant Recipients
- Uremia induces adipose tissue inflammation and muscle mitochondrial dysfunction
- Association of inflammation prior to kidney transplantation with post-transplant diabetes mellitus
- Correlation of acute tubular injury in reperfusion biopsy with renal transplant outcomes
- Parathyroid Hormone-Related Peptide-Linked Hypercalcemia in a Melanoma Patient Treated with Ipilimumab: Hormone Source and Clinical and Metabolic Correlates
- Adiponectin receptor and adiponectin signaling in human tissue among patients with end-stage renal disease
- The adipose tissue production of adiponectin is increased in end-stage renal disease
- Reverse warburg effect in a patient with aggressive B-cell lymphoma: Is lactic acidosis a paraneoplastic syndrome?
Research interests include immunological barriers in renal transplantation, sensitization and renal allograft failure management.
Publications
- Safety and Efficacy of Avacopan in Patients with Complement 3 Glomerulopathy: Randomized, Double-Blind Clinical Trial
- Deceased Donor Renal Allograft Utility in Adult Single and Multi-organ Transplantation in the United States
- Characterizing the risk of human leukocyte antigen-incompatible living donor kidney transplantation in older recipients
- Deceased-Donor Acute Kidney Injury and Acute Rejection in Kidney Transplant Recipients: A Multicenter Cohort
- Utilizing Social Media to Identify Potential Living Donors: Learning from US Living Donor Programs
- Optimising the use of telemedicine in a kidney transplant programme during the coronavirus disease 2019 pandemic
- Clinically adjudicated deceased donor acute kidney injury and graft outcomes
- Telehealth Use by Living Kidney Donor Transplant Programs During the COVID-19 Pandemic and Beyond: a Practical Approach
- Contemporary incidence and risk factors of post transplant Erythrocytosis in deceased donor kidney transplantation
- Post-transplant Diabetes Mellitus in Kidney Transplant Recipients: A Multicenter Study
- Deceased-donor acute kidney injury and bk polyomavirus in kidney transplant recipients
- COVID-19 in Solid Organ Transplantation: Disease Severity and Clinical Update
- Uromodulin to Osteopontin Ratio in Deceased Donor Urine Is Associated With Kidney Graft Outcomes
- Delayed graft function and acute rejection following HLA-incompatible living donor kidney transplantation
- Immune checkpoint inhibitor therapy-associated graft intolerance syndrome in a failed kidney transplant recipient
- Center-level Variation in HLA-incompatible Living Donor Kidney Transplantation Outcomes
- Preemptive Kidney Transplant: An Alternative to Dialysis
- Outcomes of COVID-19-positive kidney transplant recipients: A single-center experience
- An Unusual Case of Proteinuria in a Kidney Donor
- Urine Injury Biomarkers Are Not Associated with Kidney Transplant Failure
Division Faculty Peer Reviewed Publications
- Comparative analysis of Robotic-Assisted, Laparoscopic, and open radical nephrectomy: Utilization, Costs, and clinical outcomes
- Ambulatory blood pressure variability in prediction of target organ injury: the SHIP AHOY study
- Palliative Care Utilization Among Hospitalized Patients With Common Chronic Conditions in the United States
- Can artificial intelligence accurately predict the risk of hematoma expansion in intracerebral hemorrhage? A systematic review and Meta-analysis of 7,665 patients
- Perfusion Assessment in CEUS Imaging for Estimating Pancreatic Cancer Response to Sonoporation-Enhanced Chemotherapy
- A comparative evaluation of two subharmonic-aided pressure estimation (SHAPE) analysis methods
- The use of storytelling in COVID-19 vaccine promotion: A scoping review of interventions and campaigns
- Assessment of long-term endocrine sequelae of completion (2-stage) versus total (single-stage) pancreatectomy: A multi-institutional research network and single-institution analysis
- MR Imaging of Injury of the Extensor Mechanism of the Fingers
- Use of hybrid versus video-only teledermatology varies by condition: A cross-sectional study of 2064 encounters
- Intranasal delivery of extracellular vesicles derived from human bone marrow mesenchymal stem cells dampens neuroinflammation and ameliorates motor deficits in a mouse model of cortical stroke
- Implementation Factors for Wearable Fall Injury Mitigation Technology: A Framework for Technology Adoption
- Dose adjustment of the anti-seizure medications levetiracetam and lamotrigine during the postpartum period. Schedule plan, safety and efficacy
- Comparing Rhegmatogenous and Tractional Retinal Detachment in Regressed Retinopathy of Prematurity: An International, Multicenter Study
- International Consensuses and Guidelines on Diagnosing and Managing Coats Disease by the Academia Retina Internationalis (ARI), the Asia-Pacific Vitreo-retina Society (APVRS), and the Academy of the Asia-Pacific Professors of Ophthalmology (AAPPO)
- An Introduction to Regression Discontinuity Design and Potential for Application in Neurology
- Benzoxaboroles in medicinal chemistry: A structure-guided perspective on next-generation therapeutics
- Extra-anatomic right lower extremity revascularization for patient with complex arterial occlusive disease
- Does Dexmedetomidine Affect Opioid Consumption Following Orthognathic Surgery?
- Increased Risk of Postoperative Complications in Patients with Hypertension Undergoing Mohs Micrographic Surgery