Division of Nephrology
Leadership
Positions:
- Director, Division of Nephrology
- Capazzi Professor of Medicine
Organization:
Department of Medicine
Email:
Jerry.McCauley@jefferson.edu
Contact
833 Chestnut Strret
Suite 700
Philadelphia, PA 19107
Contact Number(s):
Research Activities
Our strong clinical research program, especially in the fields of acute kidney injury and hypertension, has been complemented by our growing basic research program in regulation of ion transport. We have obtained extramural funding for a broad range of clinical research projects in the areas of diabetic nephropathy, dialysis, nutrition and renal transplantation. Our NIH funded basic science research is focused on hypertension and regulation of ion transplant by FXYD proteins.
Bonita Falkner, MD
Research interests include the genetic basis of essential hypertension, insulin resistance and obesity.
Publications
- Association of Blood Pressure-Related Increase in Vascular Stiffness on Other Measures of Target Organ Damage in Youth
- Cardiovascular Risk Factors and Target Organ Damage in Adolescents: The SHIP AHOY Study
- Approach to Hypertension in Adolescents and Young Adults
- Macrophage and adipocyte interaction as a source of inflammation in kidney disease
- Primary Hypertension Beginning in Childhood and Risk for Future Cardiovascular Disease
- Pediatric and Adult Ambulatory Blood Pressure Thresholds and Blood Pressure Load as Predictors of Left Ventricular Hypertrophy in Adolescents
- The USPSTF call to inaction on blood pressure screening in children and adolescents
- Life-Course Implications of Pediatric Risk Factors for Cardiovascular Disease
- Management of Stage 1 Hypertension in Adults with a Low 10-Year Risk for Cardiovascular Disease: Filling a Guidance Gap: A Scientific Statement from the American Heart Association
- Blood pressure unknowns of sickle cell disease in children
- Maternal and gestational influences on childhood blood pressure
- What about Stage 1 Hypertension in Young Adults?
- Subclinical Systolic and Diastolic Dysfunction Is Evident in Youth with Elevated Blood Pressure
- Primordial prevention of high blood pressure in childhood an opportunity not to be missed
- Association of blood pressure level with left ventricular mass in adolescents: SHIP AHOY
- Effects of the 2017 clinical practice guidelines on hypertension in children and adolescents: A commentary
- Too Much Sugar Is Not Good for the Fetus
- Ambulatory blood pressure monitoring tolerability and blood pressure status in adolescents: The SHIP AHOY study
- Cardiac output versus total peripheral resistance a wrinkle in time
- Diagnosis, evaluation, and management of high blood pressure in children and adolescents
Maria P. Martinez Cantarin, MD
Research interests include Adipose tissue inflammation, kidney disease and transplant associated hyperglycemia.
Publications
- Macrophage and adipocyte interaction as a source of inflammation in kidney disease
- Diabetes in Kidney Transplantation
- Outcomes of COVID-19-positive kidney transplant recipients: A single-center experience
- Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects
- Correction to: Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects (Clinical Drug Investigation, (2019), 10.1007/s40261-019-00764-x)
- Kidney Support and Perioperative Care in Kidney Transplantation
- Patient Selection and Pretransplantation Care for Kidney Transplant Recipients
- Uremia induces adipose tissue inflammation and muscle mitochondrial dysfunction
- Association of inflammation prior to kidney transplantation with post-transplant diabetes mellitus
- Correlation of acute tubular injury in reperfusion biopsy with renal transplant outcomes
- Parathyroid Hormone-Related Peptide-Linked Hypercalcemia in a Melanoma Patient Treated with Ipilimumab: Hormone Source and Clinical and Metabolic Correlates
- Adiponectin receptor and adiponectin signaling in human tissue among patients with end-stage renal disease
- Reverse warburg effect in a patient with aggressive B-cell lymphoma: Is lactic acidosis a paraneoplastic syndrome?
- The adipose tissue production of adiponectin is increased in end-stage renal disease
- Relationship of adipokines with insulin sensitivity in African Americans
- Relationship of blood pressure and obesity with inflammatory cytokines among African Americans
- Variants in Genes Involved in Functional Pathways Associated with Hypertension in African Americans
- Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment
- Acute humoral rejection in a zero mismatch deceased donor renal transplant due to an antibody to an HLA-DP α
- Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: Implications for breast cancer and DCIS therapy with autophagy inhibitors
Pooja Singh, MD
Research interests include immunological barriers in renal transplantation, sensitization and renal allograft failure management.
Publications
- Optimising the use of telemedicine in a kidney transplant programme during the coronavirus disease 2019 pandemic
- Clinically adjudicated deceased donor acute kidney injury and graft outcomes
- Telehealth Use by Living Kidney Donor Transplant Programs During the COVID-19 Pandemic and Beyond: a Practical Approach
- Contemporary incidence and risk factors of post transplant Erythrocytosis in deceased donor kidney transplantation
- Deceased-donor acute kidney injury and bk polyomavirus in kidney transplant recipients
- COVID-19 in Solid Organ Transplantation: Disease Severity and Clinical Update
- Delayed graft function and acute rejection following HLA-incompatible living donor kidney transplantation
- Immune checkpoint inhibitor therapy-associated graft intolerance syndrome in a failed kidney transplant recipient
- Uromodulin to Osteopontin Ratio in Deceased Donor Urine Is Associated with Kidney Graft Outcomes
- Center-level Variation in HLA-incompatible Living Donor Kidney Transplantation Outcomes
- Outcomes of COVID-19-positive kidney transplant recipients: A single-center experience
- An Unusual Case of Proteinuria in a Kidney Donor
- Urine Injury Biomarkers Are Not Associated with Kidney Transplant Failure
- Initial skin cancer screening for solid organ transplant recipients in the United States: Delphi method development of expert consensus guidelines
- The authors reply
- Deceased-donor acute kidney injury is not associated with kidney allograft failure
- Information overload; a response to “Turn down for what? Patient outcomes associated with declining increased infectious risk kidneys”
- Tick-borne illness after transplantation: Case and review
- Hospital readmissions following HLA-incompatible live donor kidney transplantation: A multi-center study
- Kidney Support and Perioperative Care in Kidney Transplantation
Division Faculty Peer Reviewed Publications
- Sustaining large scale longitudinal interprofessional community-based health education experiences: Recommendations from three institutions
- Disease burden in patients with acute hepatic porphyria: experience from the phase 3 ENVISION study
- Notes from an epicenter: navigating behavioral clinical trials on autism spectrum disorder amid the COVID-19 pandemic in the Bronx
- Individual differences in visual evoked potential latency are associated with variance in brain tissue volume in people with multiple sclerosis: An analysis of brain function-structure correlates
- Cardiovascular outcomes of transradial versus transfemoral percutaneous coronary intervention in End-Stage renal Disease: A Regression-Based comparison
- Hospital nursing factors associated with decreased odds of mortality in older adult medicare surgical patients with depression
- Standardizing evaluation of patient-specific 3D printed models in surgical planning: development of a cross-disciplinary survey tool for physician and trainee feedback
- International consensus conference recommendations on ultrasound education for undergraduate medical students
- Altered genome-wide hippocampal gene expression profiles following early life lead exposure and their potential for reversal by environmental enrichment
- Racial difference in BMI and lung cancer diagnosis: analysis of the National Lung Screening Trial
- Predictive factors and outcomes for ibrutinib in relapsed/refractory marginal zone lymphoma: a multicenter cohort study
- Interleukin-8 produced from cancer-associated fibroblasts suppresses proliferation of the OCUCh-LM1 cancer cell line
- Multi-omic characterization of pediatric ARDS via nasal brushings
- PRMT5 activates AKT via methylation to promote tumor metastasis
- Neuromuscular junction pathology is correlated with differential motor unit vulnerability in spinal and bulbar muscular atrophy
- Bilateral upper extremity motor priming (BUMP) plus task-specific training for severe, chronic upper limb hemiparesis: study protocol for a randomized clinical trial
- A mathematical model of GLUT1 modulation in rods and RPE and its differential impact in cell metabolism
- Chimeric adenoviral (Ad5.F35) and listeria vector prime-boost immunization is safe and effective for cancer immunotherapy
- NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility
- Rationale and design of ON-TRK: a novel prospective non-interventional study in patients with TRK fusion cancer treated with larotrectinib