Research interests include the genetic basis of essential hypertension, insulin resistance and obesity.
Division of Nephrology
Research Activities
Our strong clinical research program, especially in the fields of acute kidney injury and hypertension, has been complemented by our growing basic research program in regulation of ion transport. We have obtained extramural funding for a broad range of clinical research projects in the areas of diabetic nephropathy, dialysis, nutrition and renal transplantation. Our NIH funded basic science research is focused on hypertension and regulation of ion transplant by FXYD proteins.
Publications
- Youth Blood Pressure and Target Organ Injury Markers: The SHIP AHOY Study
- Ambulatory blood pressure variability in prediction of target organ injury: the SHIP AHOY study
- Systolic Blood Pressure, Cardiovascular Health, and Neurocognition in Adolescents
- Cardiovascular Health Starts in the Womb
- Pediatric Primary Hypertension: An Underrecognized Condition: A Scientific Statement from the American Heart Association
- Development of Blood Pressure Norms and Definition of Hypertension in Children
- Insulin Resistance and Other Mechanisms of Obesity Hypertension
- Cardiovascular Risk Factors and Target Organ Damage in Adolescents: The SHIP AHOY Study
- The enigma of primary hypertension in childhood
- Association of Blood Pressure-Related Increase in Vascular Stiffness on Other Measures of Target Organ Damage in Youth
- Approach to Hypertension in Adolescents and Young Adults
- Macrophage and adipocyte interaction as a source of inflammation in kidney disease
- Primary Hypertension Beginning in Childhood and Risk for Future Cardiovascular Disease
- Pediatric and Adult Ambulatory Blood Pressure Thresholds and Blood Pressure Load as Predictors of Left Ventricular Hypertrophy in Adolescents
- The USPSTF call to inaction on blood pressure screening in children and adolescents
- Management of Stage 1 Hypertension in Adults With a Low 10-Year Risk for Cardiovascular Disease: Filling a Guidance Gap: A Scientific Statement From the American Heart Association
- Life-Course Implications of Pediatric Risk Factors for Cardiovascular Disease
- Renal Physiology for Primary Care Clinicians
- Blood pressure unknowns of sickle cell disease in children
- Maternal and gestational influences on childhood blood pressure
Research interests include Adipose tissue inflammation, kidney disease and transplant associated hyperglycemia.
Publications
- Parvovirus B19 Infection in Kidney Transplant Recipients
- TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis
- Adipose tissue metabolic changes in chronic kidney disease
- “Saving lives with nirmatrelvir/ritonavir one transplant patient at a time”
- Uremic Myopathy and Mitochondrial Dysfunction in Kidney Disease
- Macrophage and adipocyte interaction as a source of inflammation in kidney disease
- Diabetes in Kidney Transplantation
- Anemia in Chronic Kidney Disease
- Outcomes of COVID-19-positive kidney transplant recipients: A single-center experience
- Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects
- Correction to: Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects (Clinical Drug Investigation, 10.1007/s40261-019-00764-x)
- Kidney Support and Perioperative Care in Kidney Transplantation
- Patient Selection and Pretransplantation Care for Kidney Transplant Recipients
- Uremia induces adipose tissue inflammation and muscle mitochondrial dysfunction
- Association of inflammation prior to kidney transplantation with post-transplant diabetes mellitus
- Correlation of acute tubular injury in reperfusion biopsy with renal transplant outcomes
- Parathyroid Hormone-Related Peptide-Linked Hypercalcemia in a Melanoma Patient Treated with Ipilimumab: Hormone Source and Clinical and Metabolic Correlates
- Adiponectin receptor and adiponectin signaling in human tissue among patients with end-stage renal disease
- The adipose tissue production of adiponectin is increased in end-stage renal disease
- Reverse warburg effect in a patient with aggressive B-cell lymphoma: Is lactic acidosis a paraneoplastic syndrome?
Research interests include immunological barriers in renal transplantation, sensitization and renal allograft failure management.
Publications
- Safety and Efficacy of Avacopan in Patients with Complement 3 Glomerulopathy: Randomized, Double-Blind Clinical Trial
- Deceased Donor Renal Allograft Utility in Adult Single and Multi-organ Transplantation in the United States
- Characterizing the risk of human leukocyte antigen-incompatible living donor kidney transplantation in older recipients
- Deceased-Donor Acute Kidney Injury and Acute Rejection in Kidney Transplant Recipients: A Multicenter Cohort
- Utilizing Social Media to Identify Potential Living Donors: Learning from US Living Donor Programs
- Optimising the use of telemedicine in a kidney transplant programme during the coronavirus disease 2019 pandemic
- Clinically adjudicated deceased donor acute kidney injury and graft outcomes
- Telehealth Use by Living Kidney Donor Transplant Programs During the COVID-19 Pandemic and Beyond: a Practical Approach
- Contemporary incidence and risk factors of post transplant Erythrocytosis in deceased donor kidney transplantation
- Post-transplant Diabetes Mellitus in Kidney Transplant Recipients: A Multicenter Study
- Deceased-donor acute kidney injury and bk polyomavirus in kidney transplant recipients
- COVID-19 in Solid Organ Transplantation: Disease Severity and Clinical Update
- Uromodulin to Osteopontin Ratio in Deceased Donor Urine Is Associated With Kidney Graft Outcomes
- Delayed graft function and acute rejection following HLA-incompatible living donor kidney transplantation
- Immune checkpoint inhibitor therapy-associated graft intolerance syndrome in a failed kidney transplant recipient
- Center-level Variation in HLA-incompatible Living Donor Kidney Transplantation Outcomes
- Preemptive Kidney Transplant: An Alternative to Dialysis
- Outcomes of COVID-19-positive kidney transplant recipients: A single-center experience
- An Unusual Case of Proteinuria in a Kidney Donor
- Urine Injury Biomarkers Are Not Associated with Kidney Transplant Failure
Division Faculty Peer Reviewed Publications
- Assessing the effects of long-COVID on mental health in the United States: a population based study
- Artificial Intelligence Use in Medical Education: Best Practices and Future Directions
- Rates of sepsis among patients hospitalized for hidradenitis suppurativa
- Validating biomarkers of chronic whiplash-associated disorders through magnetic resonance imaging techniques
- Risk of estrogen-driven malignancies in females on 5-alpha reductase inhibitors
- Structural basis for intrinsic strand displacement activity of mitochondrial DNA polymerase
- Impact of chromatin on HIV-1 latency: a multi-dimensional perspective
- Environmental exposures and familial background alter the induction of neuropathology and inflammation after SARS-CoV-2 infection
- Pulmonary pathology in culture-negative sepsis: a potential confounder for sepsis treatment and research
- Surgical complication index for pediatric patients (SCIPP): A novel pediatric frailty index predicting postoperative complications in a study of 133 pediatric neurosurgical patients
- Evaluating Large Language Models for Automated CPT Code Prediction in Endovascular Neurosurgery
- Glucagon-like peptide-1 receptor agonists improve metabolic dysfunction-associated steatotic liver disease outcomes
- Women’s Health Considerations in Traumatic Brain Injury
- Biologic Therapies for Discogenic Pain
- Argonaute2 modulates megakaryocyte development and sex-specific control of platelet protein expression and reactivity
- The Ganglia of the Head and Neck: Clinical Relevance for the Interventional Pain Physician
- Blockchain transparency in reducing second-hand luxury shopping uncertainty and the role of price consciousness
- Ovarian Cancer G protein-coupled receptor-1 signaling bias dictates anti-contractile effect of benzodiazepines on airway smooth muscle
- VDAC2 and Bak scarcity in liver mitochondria enables targeting hepatocarcinoma while sparing hepatocytes
- Asymmetrical glymphatic dysfunction in patients with long Covid associated neurocognitive impairment- correlation with BBB disruption