Thomas Jefferson University
Sidney Kimmel Medical College
Department of Dermatology & Cutaneous Biology

Uitto, Jouni

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Jouni Uitto, MD, PhD

Contact Dr. Uitto

Bluemle Life Sciences Building, Room 450
233 South Tenth Street
Philadelphia, PA 19107

(215) 503-5785

Medical School

MD, University of Helsinki - 1970
PhD, Biochemistry - 1970


Washington University School of Medicine, MO


Hospital of University of Pennsylvania (HUP)

Board Certification


Hospital Appointment

Thomas Jefferson University Hospital

Expertise and Research Interests

Jouni Uitto, MD, PhD, has been professor of dermatology and cutaneous biology, and biochemistry and molecular biology, and chair of the Department of Dermatology and Cutaneous Biology at Jefferson Medical College, in Philadelphia, Pennsylvania, since 1986. He is also Director of the Jefferson Institute of Molecular Medicine at Thomas Jefferson University. He received his MD and PhD degrees from the University of Helsinki, Finland, and completed his residency training in dermatology at Washington University College of Medicine, St. Louis, Missouri.

Dr Uitto is internationally recognized for his research on connective tissue biochemistry and molecular biology in relation to cutaneous diseases and skin aging. Dr Uitto's publications include 610 original articles in peer-reviewed journals, 285 textbook chapters and review articles, and 907 abstracts on presentations at national and international meetings.

Dr Uitto has been the recipient of numerous national and international awards, including a Research Career Development Award from the National Institutes of Health, the Distinguished Service Award from the Dystrophic Epidermolysis Bullosa Research Association of America, the William Montagna Lectureship Award from the Society for Investigative Dermatology, the Hermann Pinkus as well as Elson B. Helwig Memorial Lectureship Awards from the American Society of Dermatopathology, the Earl of Litchfield Lectureship Award of Oxford University, The Dohi Memorial Lectureship Award from the Japanese Dermatological Society, and the Kung-Sun Oh Memorial Lectureship from Yonsei University, Seoul, Korea. In 1993, he was selected as the recipient of the Marion B. Sulzberger Memorial Award and Lectureship and was designated as the "Professor of the Year" by the American Academy of Dermatology. Dr Uitto has been awarded the prestigious Matti Äyräpää Lectureship, the highest physician-scientist award in his native country, Finland. In 1996, Dr Uitto was appointed as Anglo-American Visiting Professor of the Royal Society of Medicine, London, United Kingdom. Most recently, he was the recipient of the first SID Kligman/Frost Leadership Award presented at IID, Kyoto, Japan. He has received an Honorary Doctorate in Medicine from the University of Kuopio, the University of Oulu, and the University of Turku, Finland, as well as the Honorary Professor title from China Medical University, and Honorary Visiting Professor from the University of Helsinki.

Dr. Uitto has held office in several scientific and professional societies, including President of the Society for Investigative Dermatology, President and Chairman of the Board of Trustees, the Dermatology Foundation, Member and Chair of the General Medicine A Study Section, Board of Scientific Counselors, National Cancer Institute, and National Advisory Council, National Institute for Arthritis and Musculoskeletal and Skin Diseases, all at National Institutes of Health. Dr Uitto is also section editor of the Journal of Investigative Dermatology and is on the editorial boards of numerous peer-reviewed journals.


Most Recent Peer-Reviewed Publications

  1. Molecular Genetics and Modifier Genes in Pseudoxanthoma Elasticum, a Heritable Multisystem Ectopic Mineralization Disorder
  2. Pioneers in Dermatology and Venereology: an Interview with Professor Jouni Uitto
  3. Losartan for treatment of epidermolysis bullosa: A new perspective
  4. Keloid disorder: Fibroblast differentiation and gene expression profile in fibrotic skin diseases
  5. A phytic acid analogue INS-3001 prevents ectopic calcification in an Abcc6−/− mouse model of pseudoxanthoma elasticum
  6. Systemic CXCL10 is a predictive biomarker of vitiligo lesional skin infiltration, PUVA, NB-UVB and corticosteroid treatment response and outcome
  7. Increased level of cathelicidin (LL-37) in vitiligo: Possible pathway independent from vitamin D receptor gene polymorphism
  8. Aberrant recruitment of leukocytes defines poor wound healing in patients with recessive dystrophic epidermolysis bullosa
  9. Arrhythmogenic right ventricular cardiomyopathy in patients with biallelic JUP-associated skin fragility
  10. Coronavirus disease 2019 and epidermolysis bullosa: Report of three cases
  11. Mycophenolate mofetil treatment of an H syndrome patient with a SLC29A3 mutation
  12. Keratitis-ichthyosis-deafness syndrome: Phenotypic heterogeneity and treatment perspective of patients with p.Asp50Asn GJB2 mutation
  13. Consensus reclassification of inherited epidermolysis bullosa and other disorders with skin fragility
  14. Multidisciplinary care of epidermolysis bullosa during the COVID-19 pandemic—Consensus: Recommendations by an international panel of experts
  15. Splicing of the cake can affect the severity of epidermolysis bullosa
  16. Meeting Report: The First Global Congress on Epidermolysis Bullosa, EB2020 London: Toward Treatment and Cure
  17. Association of MTHFR C677T polymorphism with elevated homocysteine level and disease development in vitiligo
  18. The matriptase-prostasin proteolytic cascade in dermatologic diseases
  19. Molecular Therapeutics in Development for Epidermolysis Bullosa: Update 2020
  20. Research Techniques Made Simple: Whole-Transcriptome Sequencing by RNA-Seq for Diagnosis of Monogenic Disorders
  21. Linear basal cell nevus with a novel mosaic PTCH1 mutation
  22. Homozygous IL1RN Mutation in Siblings with Deficiency of Interleukin-1 Receptor Antagonist (DIRA)
  23. Genomics-based treatment in a patient with two overlapping heritable skin disorders: Epidermolysis bullosa and acrodermatitis enteropathica
  24. Meeting Report of the 4th Annual Meeting of the Chinese Society for Investigative Dermatology: Reflections on the Rise of Cutaneous Biology Research in China
  25. Epidermolysis bullosa: diagnostic guidelines in the laboratory setting