Anesthesiology Research

To solve a difficult problem in medicine, don't study it directly, but rather pursue a curiosity about nature and the rest will follow.

Roger Kornberg Nobel Prize in Chemistry, 2006

Message from the Director

Thomas Jefferson University is steeped in a history of scientific discovery and innovation. With this history in mind, our department fosters our students, residents, and faculty to pursue scholarly work at every opportunity, and at a very high level. With the help of dedicated full time research staff, including a statistician and research support personnel, our department performs an impressive amount of clinical and basic science researchers in a variety of subspecialties. Our investigators are involved in retrospective, observational research, large multi-institutional prospective and retrospective collaborations, as well as industry-funded and government-funded investigator-initiated prospective clinical trials and medical device development. Areas of special interest include acute kidney injury and cardiac surgery, hemostasis during and after cardiac surgery, optimal perioperative patient blood management practices, implementation of ERAS protocols and their impact on postoperative outcomes, and use of regional anesthesia techniques and their impact on patient outcomes and satisfaction.

With few exceptions, all research performed must involve a junior member, including residents, fellows or medical students. Their contribution is highly valued and often results in abstracts or presentations at regional or national meetings at the minimum, and frequently results in publications, including first author positions. Trainees have published in high impact journals such as Anesthesiology, Anesthesia & Analgesia, Journal of Clinical Anesthesia, Journal of Cardiothoracic and Vascular Anesthesia and Annals of Surgery. We believe that instilling a sense of curiosity and wonder in our trainees is paramount to their careers of learning, and we believe that a strong research background can only carry them further along that road.

Resident Research

The department sponsors an active clinical and laboratory based research program. Residents at the CA-2 and CA-3 levels are encouraged to initiate, complete, and present scholarly work. Residents who help with research projects are included in publications (often as first authors), and they regularly present preliminary findings at national anesthesia meetings (ASA, IARS, SOAP, ASRA, etc.). For individuals considering academic anesthesiology, this will have an important impact on their career.

Faculty Research

Clinical faculty engage in both basic science as well as clinical research. Faculty often collaborate with other departments in the medical school, as well as industry. Research efforts explore pain management, obstetric analgesia, regional anesthesia, regulation of insulin and glucose release, metabolism, measurement and function, liver transplantation, coagulation, and perioperative outcomes research using big data.

Artificial Pancreas Center

The Artificial Pancreatic Center (APC), led by Dr. Jeffrey Joseph and Dr. Marc Torjman, is a multidisciplinary team of physicians, engineers, scientists, nurses, dieticians, pharmacists and veterinarians dedicated to (1) medical device research, development, and testing, (2) education of medical students, resident physicians, fellows and faculty how to develop medical devices and perform animal/human research, and (3) research, development and clinical application of an artificial pancreas for hospitalized patients and ambulatory patients with diabetes.