Philadelphia University + Thomas Jefferson University

Edelstein, Leonard

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Leonard Edelstein, PhD

Leonard Edelstein, PhD

Contact Dr. Edelstein

1020 Locust Street
Suite 394
Philadelphia, PA 19107

(215) 955-1797
(215) 955-9170 fax


Most Recent Peer-Reviewed Publications

  1. Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth
  2. The role of platelet microvesicles in intercellular communication
  3. Identification of a functional genetic variant driving racially dimorphic platelet gene expression of the thrombin receptor regulator, PCTP
  4. TULA-2 (T-Cell Ubiquitin Ligand-2) Inhibits the Platelet Fc Receptor for IgG IIA (FcγRIIA) Signaling Pathway and Heparin-Induced Thrombocytopenia in Mice
  5. Integrative Multi-omic Analysis of Human Platelet eQTLs Reveals Alternative Start Site in Mitofusin 2
  6. MicroRNAs in platelet physiology and function
  7. Anti-miR-148a regulates platelet FcγRIIA signaling and decreases thrombosis in vivo in mice
  8. Common variants in the human platelet PAR4 thrombin receptor alter platelet function and differ by race
  9. MicroRNA expression differences in human hematopoietic cell lineages enable regulated transgene expression
  10. Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics
  11. The human platelet: Strong transcriptome correlations among individuals associate weakly with the platelet proteome
  12. Mechanism of race-dependent platelet activation through the protease-activated receptor-4 and Gq signaling axis
  13. Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c
  14. MicroRNAs in Platelet Production and Activation
  15. The complex transcriptional landscape of the anucleate human platelet.
  16. MicroRNAs in platelet production and activation
  17. Small RNAs as potential platelet therapeutics
  18. Human genome-wide association and mouse knockout approaches identify platelet supervillin as an inhibitor of thrombus formation under shear stress
  19. High-throughput screening uncovers a compound that activates latent HIV-1 and acts cooperatively with a histone deacetylase (HDAC) inhibitor
  20. MicroRNAs in platelet production and activation