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Jefferson Researchers Approved for $1 Million Funding Award from PCORI


(PHILADELPHIA)  A research team at the Sidney Kimmel Medical College at Thomas Jefferson University (TJU), led by principal investigator (PI) Kristin Rising, M.D., M.S. and co-PI Marianna LaNoue, Ph.D, has been approved for a $1 million funding award by the Patient-Centered Outcomes Research Institute (PCORI) to study novel methods for identifying patient-important outcomes for use in research.

Despite a national focus on improving the “patient centeredness” of the healthcare system, patients are seldom queried regarding their desires and preferences for what they want from the healthcare system. Researchers often use endpoints that are presumed to be important to patients rather than undergo the time consuming and technically challenging process of directly engaging patients to identify patient-centered outcomes.

Dr. Rising and her team think that in order to do patient-centered research, it is imperative to figure out how to incorporate the items that are truly important to patients. Her team has learned that these things often differ from the priorities of payers and providers.

“Patients are often minimally engaged about their priorities or needs when seeking medical care, leading to treatment plans that may not be optimally designed to meet their needs,” states PI Dr. Rising. “The goal of this work is to develop a better approach for identifying patient-important outcomes for use in the development of research and clinical interventions.”

“This project was selected for PCORI funding not only for its scientific merit and commitment to engaging patients and other stakeholders, but also for its potential to fill an important gap in our health knowledge and give people information to help them weigh the effectiveness of their care options,” said PCORI Executive Director Joe Selby, M.D., MPH. “We look forward to following the study’s progress and working with Thomas Jefferson University to share the results.”

TJU’s study was selected for PCORI funding through a highly competitive review process in which only 11.7 percent of applicants were eventually accepted. Patients, clinicians, and other stakeholders joined clinical scientists to evaluate the proposals. Applications were assessed for scientific merit, how well they will engage patients and other stakeholders, and their methodological rigor among other criteria.

The award to Drs. Rising and LaNoue has been approved pending completion of a business and programmatic review by PCORI staff and issuance of a formal award contract.

PCORI is an independent, nonprofit organization authorized by Congress in 2010. Its mission is to fund research that will provide patients, their caregivers, and clinicians with the evidence-based information needed to make better-informed healthcare decisions. For more information about PCORI’s funding, visit   


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