Matthew J. Schiewer
Assistant Professor, Departments of Urology and Cancer Biology
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Matthew J. Schiewer
Assistant Professor, Departments of Urology and Cancer Biology
Expertise & Research Interests
Dr. Schiewer’s research is focused on understanding mechanisms of disease progression and developing novel treatment strategies for genitourinary malignancies (prostate, bladder). Specifically, he is interested in examining transcriptional regulation by oncogenic transcription factors and hormone receptors; exploring therapeutic targeting of DNA repair enzymes; and understanding cancer-associated cell cycle derangement.
Publications
- Master Transcription Factor Reprogramming Unleashes Selective Translation Promoting Castration Resistance and Immune Evasion in Lethal Prostate Cancer
- Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer
- STEAP1–4 (Six-Transmembrane Epithelial Antigen of the Prostate 1–4) and Their Clinical Implications for Prostate Cancer
- A Novel Role for DNA-PK in Metabolism by Regulating Glycolysis in Castration-Resistant Prostate Cancer
- Novel Oncogenic Transcription Factor Cooperation in RB-Deficient Cancer